The United States Information Agency (USIA) was a foreign affairs agency of the U.S. government active from 1953 to 1999, dedicated to public diplomacy and international communication. The AFTOSA poster—warning against the highly contagious foot-and-mouth disease—represents a unique chapter in mid-century government graphic design. Distributed internationally (particularly in Latin America where the epidemic threatened agriculture), this rare informational poster utilizes a striking, bold graphic style to bridge language barriers and deliver a critical biosecurity message through powerful visual communication.